Thursday, June 23, 2011

Rapid-Acting Insulin

1. Humalog. Produced in the United States. The preparation is a solution for injection in vials of 10 ml and Penfill (special bottle) of 3 ml. In multiples of 5 pieces. The active ingredient is neutral lizproinsulin.

Humalog is an analogue of human insulin. The drug begins to act quickly. But the effect of it is enough korotkovremenny. This is due to the acceleration of absorption from the subcutaneous depot by storing in a solution of monomer molecular structure dizproinsulina. Humalog takes effect 15 min after injection. The total duration of 3-4 hours

By the indications for use of this drug include:

* Insulin-dependent diabetes mellitus: intolerance to other drugs, with postprandial hyperglycemia, which can not be corrected by other insulin preparations, acute subcutaneous insulin resistance;

* Insulin-independent diabetes mellitus: the cases of resistance to oral antidiabetic drugs (impaired absorption of other insulins, postprandial hyperglycemia), surgery, intercurrent diseases.

In order to pick up a dose, take into account the individual characteristics of the patient. Humalog can be injected subcutaneously, intravenously, intramuscularly. Should be administered subcutaneously, the drug, which comes in cartridges. Humalog is administered for 5-15 minutes before eating. In pure form, injections made 4-6 times a day, in combination with insulin preparations with prolonged action - 3 times a day.

Humalog, which comes in vials, mixed in one syringe with drugs that have a longer duration of action. If the transferred patients with high-performance products for animal insulin Humalog, it is necessary to adjust the dose.

Sometimes the translation from one insulin to another is carried out only in a hospital.

In Humaloga have side effects. These include hypoglycemia, hypoglycemic coma and precoma, transient disturbances of refraction, allergy, lipodystrophy.

Humalog should be stored in a refrigerator at 2-8 degrees C.

You can not freeze the bottle. Already used a bottle or cartridge can store up to 28 days at room temperature. The drug should be protected from direct exposure to heat and light.

2. Insulin-acting insulin is also NovroRapid (aspart), produced by "NovoNordisk." Its mechanism of action is the same as that of Humaloga. The drug is available in Penfill 3 ml (1 ml of 100 units).

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