Tuesday, June 28, 2011

The Average Duration of Insulin

Intermediate-acting insulins

1. Berlinsulin X foams. Produced in Germany. Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

The drug can cause side effects: hypoglycaemic state, and hypoglycemic coma, skin rash, angioedema, anaphylactic shock, flushing and itching at the injection, the introduction of lipodystrophy in place of the drug. The drug is available in the following variations.

Berlinsulin A normal pen. The active ingredient is neutral insulin, identical to human insulin. Solution for injection is available in cartridges of 1.5 ml (1 ml of 100 EA) of 5 pieces and 20 pieces. The drug takes effect within 10-15 minutes after injection, the effect lasts 68 hours daily dose injected subcutaneously in 3-4 hours.

Injections made in 10-15 minutes before eating.

X Berlinsulin basal pen. The active substance is insulin isophane protamine that is identical to a human. Suspension for injection (1 ml - 100 EA) is available in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 18 - 20 h. The daily dose of the drug is administered as a 1 - 2 subcutaneous injections for 30-45 minutes before eating.

Berlinsulin X 10/90 foam. The active substance is a neutral solution of insulin (1 ml - 10 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect after 3045 min after injection. The action continues 16-18 hours

The daily dose is divided into two injections. Injections are made for 30-45 minutes before eating.

Berlinsulin X 20/80 foam. The active substance is a neutral solution of insulin (1 ml - 20 EA) or crystalline protamine suspension (1 ml - 80 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-16 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

Berlinsulin X 30/70 foam. The active substance is a neutral solution of insulin (1 ml - 30 EA) and crystalline protamine suspension (1 ml - 30 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-15 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

Berlinsulin X 40/60 foam. The active substance is a neutral solution of insulin (1 ml - 40 EA) or crystalline protamine suspension (1 ml - 60 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-15 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

2. Insuman base. Produced in Germany. The active substance is insulin isophane protamine identical to human insulin. Suspension for injection comes in 10 ml vial, 5 pieces per pack. The drug lowers blood glucose levels. The action begins at 1 h after injection. Duration of action is 11-20 h.

Drug is given by the following testimony m:

* Insulin-dependent diabetes, diabetes during pregnancy, intolerance to other insulin preparations, the labile forms of diabetes associated with the presence of high titers of antibodies to insulin, islet cell transplantation of the pancreas;

* Insulin-independent diabetes mellitus, including resistance to oral antidiabetic drugs, surgery, intercurrent illness, pregnancy (if the ineffectiveness of diet).

The drug should be administered subcutaneously for 45-60 minutes before eating. Places inekuy should be changed. Dose is determined individually. The drug should be stored refrigerated at 2 - 8 ° C. Freezing is not allowed.

3. Protafan XM. Manufactured in Denmark. The active substance is insulin isophane protamine, identical to human insulin. Suspension for injection comes in vials of 10 ml and 3 ml Penfill. Protafan XM refers to preparations of insulin intermediate-acting. Lowers blood glucose levels. The action begins at 1.5 h after injection, lasts 24 hours

Dose is determined individually. Protafan XM is administered subcutaneously. Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

The drug can cause side effects: hypoglycaemic state, and Prek hypoglycemic coma, flushing and itching at the injection site, allergic reaction to a skin rash, angioedema, laryngeal edema, anaphylaxis. With prolonged use of the drug can lipodystrophy.

Protafan XM should be stored in a refrigerator at 2-8 degrees C. The drug must not be frozen, and exposed to sunlight.

4. Protafan XM Penfill. Manufactured in Denmark. The active substance is insulin isophane protamine, identical to human insulin. Suspension for injection (1 ml of 100 units) is available in 1.5-ml Penfill and 3 ml.

The drug is insulin, the average duration of action.

Action starts at 1.5 h after injection, lasts 24 hours

Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

Insulin dose should be determined individually. Protafan XM Penfill subcutaneously.

The drug can cause side effects: hypoglycaemic state, and Prek hypoglycemic coma, flushing and itching at the injection site, allergic reaction to a skin rash, angioedema, laryngeal edema, anaphylaxis. With prolonged use of the drug can lipodystrophy.

The drug must be refrigerated at 2 - 8 degrees C.

5. Homofan 100. Produced in Croatia. The active substance is insulin isophane protamine, identical to a human. Suspension for injection (1 ml - 100 units) is available in Penfill 1, 5 ml, pack of 5 pieces.

Homofan 100 belongs to the intermediate-acting drugs. The drug takes effect after 1.5 h after injection, the effect lasts 24 hours drug is given by the following indications:

* Insulin-dependent diabetes mellitus in children, pregnancy, intensified insulin therapy.

The drug is used 1 - 2 times a day. Time of application and dosage is determined individually. Therapy may be supplemented by short-acting insulin preparation. Homofan 100 administered subcutaneously.

The drug can cause hypoglycemia as a side effect. It is usually due to errors in the diet, irregular administration of insulin or an overdose.

Bottles should be stored in a refrigerator at 2 - 8 degrees C. Freezing of the drug is not allowed.

6. Mikstard XM Penfill. Manufactured in Denmark. The active ingredient is neutral insulin and isophane protamine insulin.

The drug reference insulin. Starts to operate in half an hour after the injection, the effect lasts 24 hours

Drug is given by the following indications:

* Insulinozavismy diabetes, diabetes during pregnancy, intolerance to other drugs insulinosoderzhaschih, labile form of diabetes is associated with the presence of high titers of antibodies to insulin, transplantauiya islet;

* Insulinnezavimy diabetes, including resistance to oral antidiabetic drugs, surgery, pregnancy (if the ineffectiveness of diet).

Dose is determined individually. The drug is administered subcutaneously.

Can have side effects: hypoglycaemic state, allergic reakuii, lipodystrophy.

Bottles should be stored in a refrigerator at 2-8 degrees C. Freezing of the drug is not allowed.

7. MonotardHM. Produced in Denmark, India. The active ingredient is Winkie suspension of insulin that is identical to human insulin. Suspension for injection comes in vials of 10 ml.

Monotard XM refers to preparations of insulin intermediate-acting. The drug takes effect after 2.5 h after subcutaneous administration, the effect lasts 24 hours

Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

Dose is determined individually.

Monotard XM can cause the following side effects: hypoglycaemic state, hypoglycemic Prek and who, allergic reactions.

Monotard XM should be stored in a refrigerator at 2-8 degrees C. Freeze preparation is impossible.

8. Homolong 40. Produced in Croatia. The active ingredient is Winkie suspension of insulin containing 300, 0, amorphous and crystalline insulin 70% identical to human insulin. Suspension for injection comes in vials of 10ml.

Homolong 40 refers to preparations of insulin expectancy. Hypoglycemic effect occurs at 2.5 h after injection, the effect lasts 22 hours

Drug is given by the following indications:
 
* Insulin-dependent diabetes mellitus, complications of insulin therapy, due to the traditional method of insulin (insulin resistance, allergic reactions, lipodystrophy post-injection), pregnancy, diabetes in childhood.

The drug is used 1 - 2 times a day. Hours and dosage is determined individually.

Homolong 40 can cause hypoglycemia, which is usually caused by errors in the diet, irregular or taking an overdose of insulin.

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