Diabetic Cure - The No Glucose, No Insulin Diabetic Remedy

Diabetes is in no way an infectious disease, yet the growing trend in statistics manifests that diabetes is spreading out globally as if it is an infectious disease.

The next decade's projection is that statistics will grow even bigger because those who are currently afflicted will be passing on the disease to their descendants as genetic deficiency. Diabetic cure if any is urgently needed to stop the increasing growth of these statistics.

The root causes have been previously established as mainly due to the inability of the insulin hormones to help in the absorption of glucose as a body nutrient. The pancreas works doubly hard to give out fresh supply of insulin as an automatic response to the rising blood sugar level.

However, the insulin hormones cannot keep up with the rate by which the pancreas produces and the resiliency by which the cells deflect the glucose substance. Diabetes type 1 takes place and finding a diabetic cure is surely a matter of urgency.

Social and environmental factors are now great contributors especially in the cases of children who have developed insulin-resistant cells due to improper diet and a sedentary lifestyle, leading to obesity.

However, majority of these children acquired their diabetes from at least one parent who was passed down with this affliction coming from several generations. Causes have been established but the diabetic cure remains elusive.

There are records however to prove that diabetes has been cured but not as a result of the $51 million worth of research granted to the American Diabetes Association.

The Proven Natural Diabetes Cure

As early as 1999, a 52-year old family doctor in Lawrence, Kansas, treated type 2 diabetic patients with an approach already popular during the depression era and with proven track record of success. The doctor's patients didn't stay sick with diabetes affliction.

The doctor's first line of cure was by totally eliminating carbohydrates from her patient's diet. In a general context, the doctor's diabetic cure bordered on reversing all the symptoms of type 2 diabetes. As one believer described it, it was only a matter of clearing out the refrigerator of all possible sources of glucose.

This may be an exaggeration but the point of the matter is that the pancreas is instigated to produce great amounts of insulin in response to the amounts of glucose present in the body.

This being the case, cells that are insulin resistant will not produce much significance in as much as there isn't a great amount of glucose to contend with. A little infusion is all that will be needed to raise the blood sugar level to normal.

The good doctor's treatment has not gained support from the American Diabetes Association despite the $51M research they have conducted since 2005. The treatment is so pure and simple, the diabetes sufferer who can't seem to find the right diabetic cure, can consider this as a way of managing his diabetes with the help of his physician and/or dietitian.

Hence, if this natural diabetic cure works, you're as good as cured.

Organic Diabetic Cure - A To Do List For Curing Diabetes

Many people are looking for a natural diabetic cure but are frustrated with the oodles of information on the internet. One website tells you to eat carbohydrates and another website tells you to stay away from carbohydrates. Who should you believe for curing diabetes?

Only recently has natural health research discovered some interesting studies about curing diabetes. If you suffer from diabetes, this may be the most important information you read all year.

By the end of this article, you will know 7 ways to start curing diabetes.

1. Watch the show "Biggest Loser" which encourages severely obese people to become healthy again! After recently watching the final episode, I was encouraged to see that one of the contestants cured diabetes naturally by eating healthy and losing weight. Start your alternative treatment by eating lean foods that are not processed. Foods that are whole (fruits, vegetables, and nuts) are a great option.

2. Exercising is so important in our 21st century lifestyle. Most of us have jobs where we sit on a chair all day. You should aim for at least 30-45 minutes of exercise daily. Did you know that 80% of people who combine dieting and exercising will almost immediately lose weight? This will help normalize blood sugar levels and eventually reverse diabetes.

3. Avoid carbohydrates which can be in many of the grains, breads and cereals you eat. You should drastically decrease you carbohydrate intake. Carbs turn into sugars after the body processes them.

4. Dark green leafy vegetables, nuts, avocados and whole grains are an excellent source of magnesium. Magnesium is known to lower blood pressure, relax the heart muscles, and control homocysteine which is known to trigger heart disease and diabetes.

5. Eating protein is important to repair cells' membranes. The cell membrane is extremely important to repair because it is responsible to eventually accepting insulin into the cell. Thus, diabetes will eventually be cured. Protein can be found in lean meats, dairy, nuts and supplementing shakes.

6. New studies also show that using cinnamon in your diet can also be beneficial. Cinnamon reduces blood glucose levels, triglycerides and LDL cholesterol which can all add up to a great natural diabetic cure. You should supplement 500 mg of cinnamon extract daily.

7. Finally, drinking water throughout the day can benefit your body in numerous ways. Water helps the body run more efficiently and also helps regenerate healthier cells which are not pre-diabetic. Men should drink about 125 ounces of water daily and women should get 100 ounces daily.

Techniques to Cure Diabetes Naturally Without Injecting Insulin

We can easily get rid of diabetes by following a balanced diet. The importance of healthy diet is very essential to control the blood sugar level in our body. We mostly see obese people suffering from this problem. The excess fats in their body causes this ailment and in order to prevent themselves from this disease. They should go for diabetic cure which includes shedding those extra pounds of weight . It can be only possible with a proper food intake and a regular exercise. Reducing extra pounds from body can be the effective tips to cure diabetes without injecting Insulin.

Regular exercise will keep high metabolism in their body hence they will lose lots of calories. Eating low fat diet will keep them healthy and sugar free can be one of the best diabetic cure.

There are three types of diabetes. They are Type 1, Type 2 and Gestational. Among them, the most common form is type 2. Surveys say that around 95 percent people in US suffers from this disease. It's very common due to excess intake of junk food and their irregular habits. Avoiding junk food can be the best diabetic cure. There are numerous effective tips to cure diabetes without injecting insulin.

Tips To Cure Diabetes Naturally Without Injecting Insulin

Exercise and diet is the best tips to cure diabetes without injecting Insulin. The change in your lifestyle for good can help you a lot as it can prove to be the best diabetic cure. A diabetic should usually take 1500-1800 calories in order to lose weight and maintain the sugar level in the body. The dynamics of carbohydrates counting plays a vital role in controlling the blood sugar level. It can prove to be the best tips to treat diabetes.

One should eat lots of green vegetables and fruits as they contain high fibers, which helps in the reduction of glucose level from the body. One should totally avoid red meat from their diet.It can be the best tips to help diabetes naturally. Injecting insulin is not a safe diabetic cure as it can lead to certain side effects in the body.

It is always advisable to make a diet list according to calories from a doctor or a dietitian. It will make your work much easier. You can have fishes, soy and poultry meat. While in fruits, you can have apples, which can be considered as best diabetic treatment .These can be the best tips to diabetes naturally without injecting insulin.

What's new in the treatment of type 1 diabetes

If one considers that the treatment of type 1 diabetes became possible in 1922 with the discovery of insulin, one must admit that for many new features have greatly increased the quality of life of these patients ( eg 1 meter in 1969, portable pumps late 70s, the insulin analogues and continuous measurement of blood glucose in the late 90s ...
 

New level of insulin.

The first inhalable insulin appeared on the market in 2005, intended primarily for people with type and type 1 diabetic adults. Because of its high price, lack of long-term studies on possible effects on the airways, difficulty of a precise dosage, this insulin has been very little interest and was withdrawn in in 2008. In late November 2007, the first oral insulin spray form has been marketed in Equador. Probably intended for people with type 2 diabetes or prediabetes, it has not yet been approved in Europe and long-term studies are not yet available. United States, a study began in 2006 trying to treat patients at high risk of diabetes with insulin capsules. The goal is to see if we can delay or prevent the onset of disease by administering insulin by the digestive tract to create a kind of tolerance and thus calm the immune system. Prevention of type 1 diabetes is not so far, the results of this study (in a few years) are eagerly awaited. However, it has already been proven that these insulin capsules will not be used to treat diabetes already said.

Vaccination

A hot topic in diabetes research for GAD65 vaccination. The GAD65 protein is beta cells. Diabetic type 1 there are antibodies that destroy certain proteins, often also GAD65. The idea of this vaccine is to keep as long as possible the production of insulin by beta cells by deflecting action of immune antibodies to the injected proteins. First results seem promising in Sweden and large-scale studies are planned in Europe in 2008. The Swedish study suggests that most are vaccinated sooner a person in whom diabetes has just been declared, the more we come to preserve beta cell.

Prevention (of disease onset)

These measures include also studies of oral insulin (see "insulin") In Europe, several countries are currently involved in "the study pre Point", in which we try to prevent the formation of destructive beta-cell antibodies by administration of insulin as a spray or powder in the diet of children at high risk of diabetes (which could have a hypoglycemic effect in those already diabetic). The hypothesis is that insulin may stimulate the immune system by inducing an immune response designed to protect cells against beta-destruction. The study has just begun, but similar studies in the U.S. seem promising.

Transplants

We are in the hot topic of stem cell therapy. The goal of research in the field of transplantation is a cure for diabetes by transplanting functional beta cells, the major problem is however the lack of organ donors. In recent years, a new method was developed: the culture of Beta cells from stem cells (= cells that can renew themselves indefinitely and give specialized cells by cell differentiation). We distinguish embryonic stem cells and adult stem cells. Studies in mice have allowed to grow insulin-producing cells from embryonic or adult stem cells which, transplanted into diabetic mice, have improved even normalization of blood glucose. Unfortunately, these experiences are only a stage animal and research on human embryonic cells still raises many ethical issues well justified. Similarly, studies of autologous stem cells (in Germany, Brazil) are very interesting. In this case, is transplanted to the patient's own stem cells that will be responsible for insulin production and replace insulin injections. The initial results seem positive, but research is still needed.

Measurement of continuous glucose

In 2006, the techniques of continuous glucose measurement have become increasingly efficient and allow the patient to directly read glucose values measured
in the subcutaneous tissue that appear on the device using a transmitter without cable, whose size has also fallen sharply, which enhances comfort, especially in children. The sensors can remain in place 3-6 days. Recently, the RealTime Paradigm insulin pump was also placed on the market in Luxembourg, (not yet repaid). This pump is combined with a continuous glucose monitor, the patient must wear two subcutaneous catheters (one for the administration of insulin to a glucose sensor). He can see glucose values on the pump which also warns if glucose is trying to climb or fall and emits alarm signals in case of hypo-or hyperglycemia. All these study results and progress in research lead us slowly towards the dream of a cure diabetes, but the road is still long! However, we can also see that all these small steps since the discovery of insulin allows diabetics to continuously improve their quality of life.

Insulin Resistance Syndrome

Fairly common condition that destroys the health of the age of 45 years - the so-called metabolic syndrome.

Metabolic syndrome (syndrome X, insulin resistance syndrome) - a sum of a large number of interrelated pathological factors that create conditions for the emergence and development of cardiovascular disease and insulin-dependent diabetes.

This syndrome first identified an American scientist Gerald Riven. In the late 80s of last century D. Riven proved the existence of insulin resistance syndrome (syndrome Rivena later called), which defines the concomitant development of hypertension, diabetes mellitus type 2, hyperlipidemia and atherosclerosis.

Namely insulin resistance and hypoglycemia are at the root factors of metabolic syndrome.

The loss of cell sensitivity to insulin - insulin resistance develops against the background of obesity, which violates the distribution of glucose and hypoglycemia develops. Scientists have proved that the degree of insulin resistance is directly proportional to the amount of excess fat. With the accumulation of fat in the body fat cells gradually grow in size. The greater the fat cell in size, the less it responds to the hormone insulin. Thus, insulin inhibits the process is less breakdown of fat into fatty acids. As a result, accumulate in the blood free fatty acids.

In accordance with the laws of interaction products of metabolism - glucose and aliphatic acids - the muscle cells of the liver and stimulates the oxidation of free fatty acids, and thus prevent the normal transport of glucose - insulin resistance occurs. In this situation, starting the pancreas to secrete insulin in an even larger quantities, resulting in hypoglycemic disease.

As a result, we have the following chain: physical inactivity, obesity, and abundance in the diet of fatty foods lead to insulin resistance of body tissues. Insulin resistance leads to hyperinsulinism (hypoglycemia). A hyperinsulinism is a cause of hypertension, dyslipidemia, atherosclerosis, coronary heart disease and diabetes type 2. Thus developing metabolic syndrome.

World medical practice suggests that metabolic syndrome is a major factor in the extreme aggravation of these pathologies, raising their overall risk. Metabolic syndrome, sick almost every fifth person aged and elderly vozrasta.Poetomu today so it is important to diagnose early and effective treatment.

Markers of metabolic syndrome: abdominal obesity, hypertension, dyslipidemia. All these markers typically originate from the tissue to insulin resistance and hypoglycemia.

Metabolic syndrome consists of the following abnormalities:
- High blood pressure - more than 170/100 mm Hg. Art.
- Hyperlipidemia: increased concentration of fat in the blood (more than 1.72 millimoles / liter) and decreased concentration of HDL cholesterol - less than 0.9 millimoles / liter for men and less than 1 mmol / liter for women.
- Overweight: BMI - over 30 kg/m2, or the ratio of waist circumference to hip circumference greater than 0.9 in men and 0.86 in women.
- Hyper Albuminuria (concentration of albumin in the urine - a 0.02mg/ml).
- Insulin-dependent diabetes.

According to generally accepted rules of medical suffering from metabolic syndrome are at high risk of serious heart disease and circulatory system, as well as renal pathology.

Patients with metabolic syndrome to lead healthy lives, to establish a healthy food system with effective dietary supplements.

It should be noted that pharmacological drugs that are often used to control blockers in this situation are not welcome, because they exacerbate the imbalance of metabolism and provoke damage the glomerular apparatus of the kidneys and increase resistance to insulin.

Medicine today has detailed data on metabolism at the intracellular level, and allows you to regulate it in various diseases. Therefore, in recent years people are increasingly interested in various biologically active supplements containing active ingredients: fermentarnye substrates, amino acids, enzymes, cell membrane stabilizers, antioxidants, catalysts education RNA, DNA and other nucleic acids.

So now gaining popularity dietary supplements Tianshi Corporation, which are composed of vitamins, macro-and micronutrients, dietary flavonoids (fat eel Biotsink, Holikan, Biocalcium). Receiving the substance, the body is able to synthesize the most important structures that support health and normal activity (enzymes, peptides, neurotransmitters, nucleic acids, etc.).

The Average Duration of Insulin

Intermediate-acting insulins

1. Berlinsulin X foams. Produced in Germany. Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

The drug can cause side effects: hypoglycaemic state, and hypoglycemic coma, skin rash, angioedema, anaphylactic shock, flushing and itching at the injection, the introduction of lipodystrophy in place of the drug. The drug is available in the following variations.

Berlinsulin A normal pen. The active ingredient is neutral insulin, identical to human insulin. Solution for injection is available in cartridges of 1.5 ml (1 ml of 100 EA) of 5 pieces and 20 pieces. The drug takes effect within 10-15 minutes after injection, the effect lasts 68 hours daily dose injected subcutaneously in 3-4 hours.

Injections made in 10-15 minutes before eating.

X Berlinsulin basal pen. The active substance is insulin isophane protamine that is identical to a human. Suspension for injection (1 ml - 100 EA) is available in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 18 - 20 h. The daily dose of the drug is administered as a 1 - 2 subcutaneous injections for 30-45 minutes before eating.

Berlinsulin X 10/90 foam. The active substance is a neutral solution of insulin (1 ml - 10 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect after 3045 min after injection. The action continues 16-18 hours

The daily dose is divided into two injections. Injections are made for 30-45 minutes before eating.

Berlinsulin X 20/80 foam. The active substance is a neutral solution of insulin (1 ml - 20 EA) or crystalline protamine suspension (1 ml - 80 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-16 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

Berlinsulin X 30/70 foam. The active substance is a neutral solution of insulin (1 ml - 30 EA) and crystalline protamine suspension (1 ml - 30 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-15 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

Berlinsulin X 40/60 foam. The active substance is a neutral solution of insulin (1 ml - 40 EA) or crystalline protamine suspension (1 ml - 60 EA). Suspension for injection comes in cartridges of 1.5 ml of 5 and 20 pieces per pack. The drug takes effect 30-45 minutes after injection. The action continues 14-15 hours daily dose is divided into two injections. The drug is injected 30-45 minutes before eating.

2. Insuman base. Produced in Germany. The active substance is insulin isophane protamine identical to human insulin. Suspension for injection comes in 10 ml vial, 5 pieces per pack. The drug lowers blood glucose levels. The action begins at 1 h after injection. Duration of action is 11-20 h.

Drug is given by the following testimony m:

* Insulin-dependent diabetes, diabetes during pregnancy, intolerance to other insulin preparations, the labile forms of diabetes associated with the presence of high titers of antibodies to insulin, islet cell transplantation of the pancreas;

* Insulin-independent diabetes mellitus, including resistance to oral antidiabetic drugs, surgery, intercurrent illness, pregnancy (if the ineffectiveness of diet).

The drug should be administered subcutaneously for 45-60 minutes before eating. Places inekuy should be changed. Dose is determined individually. The drug should be stored refrigerated at 2 - 8 ° C. Freezing is not allowed.

3. Protafan XM. Manufactured in Denmark. The active substance is insulin isophane protamine, identical to human insulin. Suspension for injection comes in vials of 10 ml and 3 ml Penfill. Protafan XM refers to preparations of insulin intermediate-acting. Lowers blood glucose levels. The action begins at 1.5 h after injection, lasts 24 hours

Dose is determined individually. Protafan XM is administered subcutaneously. Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

The drug can cause side effects: hypoglycaemic state, and Prek hypoglycemic coma, flushing and itching at the injection site, allergic reaction to a skin rash, angioedema, laryngeal edema, anaphylaxis. With prolonged use of the drug can lipodystrophy.

Protafan XM should be stored in a refrigerator at 2-8 degrees C. The drug must not be frozen, and exposed to sunlight.

4. Protafan XM Penfill. Manufactured in Denmark. The active substance is insulin isophane protamine, identical to human insulin. Suspension for injection (1 ml of 100 units) is available in 1.5-ml Penfill and 3 ml.

The drug is insulin, the average duration of action.

Action starts at 1.5 h after injection, lasts 24 hours

Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

Insulin dose should be determined individually. Protafan XM Penfill subcutaneously.

The drug can cause side effects: hypoglycaemic state, and Prek hypoglycemic coma, flushing and itching at the injection site, allergic reaction to a skin rash, angioedema, laryngeal edema, anaphylaxis. With prolonged use of the drug can lipodystrophy.

The drug must be refrigerated at 2 - 8 degrees C.

5. Homofan 100. Produced in Croatia. The active substance is insulin isophane protamine, identical to a human. Suspension for injection (1 ml - 100 units) is available in Penfill 1, 5 ml, pack of 5 pieces.

Homofan 100 belongs to the intermediate-acting drugs. The drug takes effect after 1.5 h after injection, the effect lasts 24 hours drug is given by the following indications:

* Insulin-dependent diabetes mellitus in children, pregnancy, intensified insulin therapy.

The drug is used 1 - 2 times a day. Time of application and dosage is determined individually. Therapy may be supplemented by short-acting insulin preparation. Homofan 100 administered subcutaneously.

The drug can cause hypoglycemia as a side effect. It is usually due to errors in the diet, irregular administration of insulin or an overdose.

Bottles should be stored in a refrigerator at 2 - 8 degrees C. Freezing of the drug is not allowed.

6. Mikstard XM Penfill. Manufactured in Denmark. The active ingredient is neutral insulin and isophane protamine insulin.

The drug reference insulin. Starts to operate in half an hour after the injection, the effect lasts 24 hours

Drug is given by the following indications:

* Insulinozavismy diabetes, diabetes during pregnancy, intolerance to other drugs insulinosoderzhaschih, labile form of diabetes is associated with the presence of high titers of antibodies to insulin, transplantauiya islet;

* Insulinnezavimy diabetes, including resistance to oral antidiabetic drugs, surgery, pregnancy (if the ineffectiveness of diet).

Dose is determined individually. The drug is administered subcutaneously.

Can have side effects: hypoglycaemic state, allergic reakuii, lipodystrophy.

Bottles should be stored in a refrigerator at 2-8 degrees C. Freezing of the drug is not allowed.

7. MonotardHM. Produced in Denmark, India. The active ingredient is Winkie suspension of insulin that is identical to human insulin. Suspension for injection comes in vials of 10 ml.

Monotard XM refers to preparations of insulin intermediate-acting. The drug takes effect after 2.5 h after subcutaneous administration, the effect lasts 24 hours

Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

Dose is determined individually.

Monotard XM can cause the following side effects: hypoglycaemic state, hypoglycemic Prek and who, allergic reactions.

Monotard XM should be stored in a refrigerator at 2-8 degrees C. Freeze preparation is impossible.

8. Homolong 40. Produced in Croatia. The active ingredient is Winkie suspension of insulin containing 300, 0, amorphous and crystalline insulin 70% identical to human insulin. Suspension for injection comes in vials of 10ml.

Homolong 40 refers to preparations of insulin expectancy. Hypoglycemic effect occurs at 2.5 h after injection, the effect lasts 22 hours

Drug is given by the following indications:
 

* Insulin-dependent diabetes mellitus, complications of insulin therapy, due to the traditional method of insulin (insulin resistance, allergic reactions, lipodystrophy post-injection), pregnancy, diabetes in childhood.

The drug is used 1 - 2 times a day. Hours and dosage is determined individually.

Homolong 40 can cause hypoglycemia, which is usually caused by errors in the diet, irregular or taking an overdose of insulin.

Short-Acting Insulins

1. Aktranid XM. This drug produced in India, Denmark. The active ingredient is a monocomponent neutral insulin solution is identical to human insulin. Solution for injection comes in 3 mL Penfill and 06ychyyx 10 ml vials. 1 ml contains 100 IU of the active substance.

Actrapid HM - a short-acting insulin preparation. Its action starts in half an hour after the injection, lasts 6 - 8 pm

By the indications for this drug include:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic means, partial resistance to these drugs (combination therapy), intercurrent illness, opera1JII, pregnancy (if the ineffectiveness of diet).



In addition, the drug can be assigned to patients with diabetic ketoacidosis, hyperosmolar coma, coma ketoatsidoticheskoy, if you are allergic to animal insulin preparations.

Actrapid HM administered subcutaneously, intravenously, intramuscularly. The dose is determined individually. If Actrapid HM used in their pure form, it can be assigned to three times a day, sometimes 5-6 times a day. If the patient is transferred to the bull or mixed insulin, the dose must adjust.

When you receive Actrapid hm may experience the following side effects: hypoglycemia, allergic reactions, disorders refraK1JII, which are transient.

The drug should be stored in a refrigerator at 2-8 degrees C. Do not freeze bottles. If the drug is stored at room temperature, it should be used within 6 weeks.



2. Actrapid HM Penfill. Manufactured in Denmark. The active ingredient is a monocomponent neutral insulin solution, identical to human insulin. The solution is to ineK1JY Penfill of 1.5 ml and 3 ml injection pens.

The drug belongs to a short-acting insulin.

Starts to operate in half an hour after the administration of the body, acts 6-8 hours Indications are the same as when using Actrapid HM. The drug is administered subcutaneously. The dose is determined individually. Storage conditions are similar to Actrapid HM.

3. Insuman Rapid. Produced in Germany. The active substance is a neutral solution of insulin that is identical to human insulin. Solution for injection is available in vials x 10 ml, 5 pieces per pack, in cartridges for injection pens.

Insuman Rapid refers to preparations of insulin with a rapid onset and short duration of action. Leads to a rapid decrease in blood glucose levels. The drug takes effect within half an hour after administration.

The action continues 5.8 hours

By the indications for use Insumana Rapida include:

* 1 diabetes type-two;

* Diabetes mellitus type 2: resistance to oral hypoglycemic medications, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet).

Dose is determined individually. The drug should be administered subcutaneously or intravenously. Subcutaneous drug is administered for 15 - 20 minutes before eating.

Can have side effects: hypoglycemia, hypoglycemic coma and precoma, allergic reaction.

4. Homoral 40. Produced in Croatia. The active substance is a neutral solution of insulin that is identical to human insulin. The drug is available in vials of 1 ml O. Homoral 40 - a short-acting insulin preparation. Reduction in blood glucose levels begin half an hour after injection. Effect of the drug an average of 8 hours.

By reading meters for use Homorala 40 include:

* Insulin-dependent diabetes mellitus. Particularly effective drug in cases where urgent intervention is necessary, such as diabetic coma and precoma, surgery, pregnancy, childhood and adolescence.

Homoral 40 is used two or more times per day. The dose is determined individually. The drug should be administered intravenously, intramuscularly, subcutaneously. Homoral can be mixed with other drugs to human insulin.

Homoral 40 can cause hypoglycemia as a side effect. Such a condition can result from errors in the assigned diet, irregular administration of insulin or a drug overdose.

5. Homoral 100. Produced in Croatia. The active substance is a neutral solution of insulin that is identical to human insulin. The drug is available in Penfill of 1.5 ml, in multiples of 5 pieces. Indications for use of this drug are similar to the previous one. Time and dosage is determined individually. By the side effect is hypoglycemia.

6. Humulin regular. Produced in India. The active substance is identical to human insulin. The drug is available in bottles of 10 ml and 3 ml Penfill (1 ml - 100 U).

Short-acting. It is based on recombinant DNA, the exact number of amino acid human insulin. The drug takes effect within 10 min after injection, the effect lasts 6-8 h.

By the indications for the use of regular Humulin include:

* Insulin-dependent form of diabetes: hyperosmolar coma, preparation for surgery, trauma, acute infections.

The dose is determined individually, focusing on the patient's condition. In pure form, the drug is administered 3-4 times per day.

Humulin regular can cause such side effects, insulin resistance, hypersensitivity reaction.

The drug is contraindicated if you are sensitive to it, as well as hypoglycemia.

7. Berlinsulin HU-40. Produced in Germany. Drug is given by the following indications:

* Diabetes mellitus type 1;

* Diabetes mellitus type 2: stage of resistance to oral hypoglycemic drugs, partial resistance to these drugs, intercurrent illness, surgery, pregnancy (if the ineffectiveness of diet), diabetic coma.

The drug is available in the following flavors:

Berlinsulin A normal V-40. The active ingredient is neutral insulin identical to human insulin. Solution for injection in vials of 10 ml. The drug takes effect within 10-15 minutes after injection, the duration of 6-8 hours daily dose should be administered subcutaneously in 3-4 hours. In diabetic coma drug is administered within the vein but.

X Berlinsulin basal U-40. The active substance is insulin isophane protamine, identical to human insulin. Suspension for injection comes in vials of 10 ml. Takes effect 30-45 minutes after injection, the duration of 18-20 hours daily dose is administered as a 1 - 2 subcutaneous injections.

Berlinsulin X 10/90 U-40. The active substance is a neutral solution of insulin (1 ml - 4 EA) or crystalline protamine suspension (1 ml - 36 EA). Suspension for injection comes in vials of 10 ml. The daily dose is divided into two injections, 2 / 3 doses should be administered in the morning, 1 / 3 dose - in the evening. Injections are made for 30-45 minutes before eating.

These drugs can cause side effects: Hypoglycemic coma, hypoglycemic condition, skin rash, angioedema, anaphylactic shock.

Injection site may occur flushing, itching. With prolonged use at injection sites can be observed lipodystrophy.

Berlinsulin X 20/80 U-40. The active substance is a neutral solution of insulin (1 ml - 8 EA) or crystalline protamine suspension (1 ml - 32 EA).

Suspension for injection comes in a bottle of 10 ml. The drug takes effect 30-45 minutes after injection, the effect lasts 14-16 hours.

Dosage and side effects are similar to the previous preparation.

Berlinsulin X 30/70 U-40. The active substance is a neutral solution of insulin (1 ml - 12 EA) or crystalline protamine suspension (1 ml - 28 EA). Suspension for injection comes in vials of 10 ml. The drug takes effect 30-45 minutes after injection, the effect lasts 14-15 hours.

Dosage and side effects are similar to the previous preparation.

Berlinsulin X 40/60 U-40. The active substance is a neutral solution of insulin (1 ml - 16 EA) or crystalline protamine suspension (1 ml - 24 EA). Suspension for injection in vials of 10 ml. The drug takes effect 30-45 minutes after injection, the effect lasts 14-15 hours Dosage and side effects are similar to the previous preparation.

Rapid-Acting Insulin

1. Humalog. Produced in the United States. The preparation is a solution for injection in vials of 10 ml and Penfill (special bottle) of 3 ml. In multiples of 5 pieces. The active ingredient is neutral lizproinsulin.

Humalog is an analogue of human insulin. The drug begins to act quickly. But the effect of it is enough korotkovremenny. This is due to the acceleration of absorption from the subcutaneous depot by storing in a solution of monomer molecular structure dizproinsulina. Humalog takes effect 15 min after injection. The total duration of 3-4 hours

By the indications for use of this drug include:

* Insulin-dependent diabetes mellitus: intolerance to other drugs, with postprandial hyperglycemia, which can not be corrected by other insulin preparations, acute subcutaneous insulin resistance;

* Insulin-independent diabetes mellitus: the cases of resistance to oral antidiabetic drugs (impaired absorption of other insulins, postprandial hyperglycemia), surgery, intercurrent diseases.

In order to pick up a dose, take into account the individual characteristics of the patient. Humalog can be injected subcutaneously, intravenously, intramuscularly. Should be administered subcutaneously, the drug, which comes in cartridges. Humalog is administered for 5-15 minutes before eating. In pure form, injections made 4-6 times a day, in combination with insulin preparations with prolonged action - 3 times a day.

Humalog, which comes in vials, mixed in one syringe with drugs that have a longer duration of action. If the transferred patients with high-performance products for animal insulin Humalog, it is necessary to adjust the dose.

Sometimes the translation from one insulin to another is carried out only in a hospital.

In Humaloga have side effects. These include hypoglycemia, hypoglycemic coma and precoma, transient disturbances of refraction, allergy, lipodystrophy.

Humalog should be stored in a refrigerator at 2-8 degrees C.

You can not freeze the bottle. Already used a bottle or cartridge can store up to 28 days at room temperature. The drug should be protected from direct exposure to heat and light.

2. Insulin-acting insulin is also NovroRapid (aspart), produced by "NovoNordisk." Its mechanism of action is the same as that of Humaloga. The drug is available in Penfill 3 ml (1 ml of 100 units).

Insulin Shock Therapy

There are three basic modes of insulin therapy. They each have their advantages and disadvantages.

In a healthy person insulin secretion occurs constantly and is about 1 IU of insulin in 1 h, the so-called basal or background secretion. During the meal, a rapid (bolus) insulin concentrations increase many times over. Stimulated insulin secretion is approximately 1-2 units for every 10 grams of carbohydrates. While maintaining a constant balance between the concentration of insulin and the need for it on the basis of feedback.

A patient with diabetes mellitus type 1 requires insulin replacement, which would mimic insulin secretion under physiological conditions. Need to use different types of insulin at different times. To achieve satisfactory results by a single introduction of insulin in patients with diabetes type 1 is impossible. Injections can be from 2 to 5-6 times a day. The more injections, the treatment of insulin more close to physiological. In patients with diabetes mellitus type 2 with preserved beta cell function rather one-, two-time insulin to maintain the state for compensation.

1. Fixed-dose regime (regular insulin)

Treatment of diabetes in this mode assumes that the number of units of bread (carbohydrate) every day at every meal has remained relatively constant. Accordingly, doses of insulin are also constant (fixed). Before eating, we introduce a short insulin, insulin prolonged shooting up for a night or two times a day.

The total daily dose (short and extended) of insulin may reach 0.6-1.2 U / kg.

Insulin therapy in this mode is ineffective. Blood sugar with this method of treatment varies considerably from high to low values. Obtain compensation for diabetes, using the fixed-dose regime is almost impossible. But this option is included in the treatment of diabetes (especially the elderly), when you have to make compromises.

2. Intensive insulin therapy (base-bolus regime)

To simulate normal daily (basal) secretion of insulin 2 times a day (12 hours), prolonged insulin is introduced, usually a morning dose of insulin is somewhat greater than at bedtime.

To create a nutritional peak, "teasing" short insulin before each meal (3 meals - 3 short-bolus insulin). To calculate the dose of short-insulin is necessary to know their blood glucose before each meal and the planned number of units of grain at the reception.

Intensive insulin therapy simulates the normal functioning of the pancreas and consistent way of life. It is understandable optimistic motto "diabetes - is not a disease but a way of life" when the patient's freedom is not restricted, no restriction in the diet does not exist (as you eat, how much insulin was introduced, if eaten more than the estimated dose, just need to pin insulin).

3. Combined insulin

Combines diet, oral hypoglycemic drugs and insulin injections prolonged for a night or two times a day (usually 12 units in the morning and 8 units at bedtime).

Treatment of type 2 diabetes provides excellent results in most patients, if we use the following combination: insulin glargine (Lantus) once in the morning or evening, sulfonylurea + 3rd generation (MW Diabeton or Amaryl) once in the morning + (with obesity), metformin.

Vials short-acting insulin Actrapid and NovoRapid 10 ml vial at a concentration 100ME/ml.

Insulin therapy has the task of the maximum possible compensation of carbohydrate metabolism, prevention of hypo-and hyperglycemia, and thus prevent complications of diabetes. Insulin treatment is vital for people with diabetes type 1 and can be used in some situations for people with diabetes type 2.

Indications for the use of insulin therapy:

    Diabetes mellitus type 1
    Ketoacidosis, diabetic hyperosmolar.
    Pregnancy and childbirth in diabetes mellitus.
    A significant decompensation of diabetes mellitus type 2.
    Lack of effect of treatment of other ways of diabetes type 2.
    A significant reduction in body weight in diabetes mellitus.
    Diabetic nephropathy.

Currently, there are a lot of insulin, which differ in duration of action (ultrashort, short, medium and extended), the degree of purification (monocomponent), species specificity (human, porcine, bovine, genetically engineered, etc.)

In Russia, the insulin derived from cattle, derived from consumption, it is associated with more side effects when applied. Quite often when they are administered allergic reactions, lipodystrophy, insulin resistance develops.

News in Diabetes Care - A Compact Pancreas

According to experts of diabetes is not just a disease, and this subculture that unites people around the world. According to official reports by WHO of diabetic patients of the second type only in Russia amounts to 2.5 million people, but many experts say this figure is underestimated by 2-3 times.

Against this sad picture there is good news. In 69 conference of the American Diabetes Association (ADA) were presented reports on the use of so-called artificial pancreas. Tests were conducted on patients with diabetes first type, in the process of insulin device is held constant (a 5-minute intervals), and change the glycemic patterns of patients monitored by sensors. The whole system is connected to a laptop computer, which conducts measurements of about 200 times a day (instead of 5-10 at the current opportunities).

The information obtained reflects the real picture about the content of glucose in the blood of a patient, the changes of blood glucose, so it is possible to monitor therapy online. In addition, the system has the ability to control insulin, thereby eliminating any possibility of an overdose.

According to the developers, the system will be quite compact and the size will not exceed a modern mobile phone (existing design of an artificial pancreas in size comparable to a laptop).

Postprandial glucose sensors increase in the body, with the system enters in excess of basal insulin needs. Normalization of blood glucose occurs after a few hours, eliminating the risk of hypoglycemia.

Experts expect the approval of the FDA study for 2-3 months, after this period will be sure to talk about the future of this truly useful development for the treatment of diabetes.

Which Insulin to Use?

All those for whom the familiar meaning of the words "diabetes" does not know firsthand about the classification, under which distinguished several types of insulin depending on the duration of its action. But while few people before the end made the choice of which of these species is suitable for him. I'll try to highlight the main positive aspects of each type.

To begin, recall that carbohydrates can be ingested in two ways: through food and the liver. For the fact that insulin is produced in the right proportions, is responsible pancreas. A healthy body is constantly highlights the short-acting insulin, the patient as a person has to follow the flow of this process and try to simulate it in time. Usually for this purpose injections of short and long-acting combined.

In medicine, we know two of these combination: Intensify and conventional insulin therapy. The first is the introduction of short-acting injections on the assimilation XE immediately before the patient is going to eat an average of 3 times a day. The traditional combination also implies the introduction of a diabetic one or two injections before meals: usually in the morning and before dinner.

The choice of ways to keep your blood sugar depends on the condition of the patient, but I note that in recent times in medicine is increasingly favored intensified insulin therapy. The fact that it is not necessary to maintain a strict diet, which is not the traditional scheme. I recall that during its observance, will eat lunch at a certain time. Namely, in the peak time when insulin is introduced in the morning reached its climax of his actions. Otherwise, the patient may be caused by hyperglycemia.

Often there is one more question: how much insulin to be discharged into the body at any given time of day? To answer it clearly is not possible, since it is strictly an individual process. Determine the dose of insulin required can be empirically - constantly monitoring blood sugar levels. But here's what you can state with confidence is that to date medicines can not help feeling sick with diabetes mellitus itself is defective. And correct treatment of the day, keep the same daily life as healthy people.